医学
大流行
2019年冠状病毒病(COVID-19)
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
公共卫生
重症监护医学
2019-20冠状病毒爆发
免疫系统
病毒学
逃避(道德)
冠状病毒
软件部署
免疫学
传染病(医学专业)
疾病
爆发
护理部
病理
操作系统
计算机科学
作者
Akira Shishido,Ashley H. Barnes,Shivakumar Narayanan,Joel V Chua
出处
期刊:Seminars in Respiratory and Critical Care Medicine
[Georg Thieme Verlag KG]
日期:2023-01-16
卷期号:44 (01): 143-172
被引量:3
标识
DOI:10.1055/s-0042-1759779
摘要
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has led to an unprecedented public health crisis. The collective global response has led to production of multiple safe and effective vaccines utilizing novel platforms to combat the virus that have propelled the field of vaccinology forward. Significant challenges to universal vaccine effectiveness remain, including immune evasion by SARS-CoV-2 variants, waning of immune response, inadequate knowledge of correlates of protection, and dosing in special populations. This review serves as a detailed evaluation of the development of the current SARS-CoV-2 vaccines, their effectiveness, and challenges to their deployment as a preventive tool.
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