射血分数保留的心力衰竭
心力衰竭
医学
射血分数
心脏病学
赛马鲁肽
内科学
炎症
肥胖
糖尿病
2型糖尿病
内分泌学
利拉鲁肽
作者
Subodh Verma,Barry A. Borlaug,Javed Butler,Melanie J. Davies,Dalane W. Kitzman,Mark C. Petrie,Sanjiv J. Shah,Nitish K. Dhingra,Mikhail Kosiborod
出处
期刊：Cell Metabolism
[Cell Press]
日期：2023-10-01
卷期号：35 (10): 1681-1687
被引量：8
标识
DOI：10.1016/j.cmet.2023.08.003
摘要
In the STEP-HFpEF trial, 2.4 mg semaglutide produced marked improvements in heart failure-related symptoms, physical limitations, and exercise function, and reduced inflammation and body weight in individuals with obesity HFpEF phenotype. These data usher in a new paradigm of targeting obesity as a therapeutic strategy in HFpEF.
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