化学
钌
炔烃
部分
催化作用
氢化物
亲核细胞
有机化学
组合化学
药物化学
金属
作者
Haowei Ding,Ken Sakata,Shogo Kuriyama,Yoshiaki Nishibayashi
出处
期刊:Organometallics
[American Chemical Society]
日期:2020-05-28
卷期号:39 (11): 2130-2134
被引量:12
标识
DOI:10.1021/acs.organomet.0c00187
摘要
Ruthenium-catalyzed propargylic reduction of propargylic alcohols bearing a terminal alkyne moiety is accomplished by using Hantzsch ester as a nucleophilic hydride source. A variety of secondary and tertiary propargylic alcohols are reduced to the corresponding propargylic reduced products such as 1-alkynes in excellent yields. Some mechanistic studies indicate that ruthenium–allenylidene complexes may work as key reactive intermediates.
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