Observation of Anesthetic Effects of Ketamine Combined with Thiopentalum Natricum on Wuzhishan Minipigs

To compared anesthetic effects of ketamine combined with thiopentalum natricum on Wuzhishan minipigs.40 healthy minipigs were divided into two groups: anesthesia by ketamine(n=20,group 1) or ketamine combined with thiopentalum natricum(n=20,group 2).All minipigs underwent muscular or venous injection with these chemicals.It was found that anesthesia of group 2 maintained(198.0±32.7) min,anesthesia of group1 maintained(104.0±17.3) min,and group 2 showed better anaesthesia effect.Furthermore,the combined anesthetization could improve the anesthetic effect: increase muscular relaxation,do not interfere with respiration and cycle system,and show prolonged and more stable anesthesia with quick resuscitation.Thus,ketamine combined with thiopentalum natricum appears to be a perfect method for the prolonged surgery of experimental minipigs.