多导睡眠图
医学
艾普沃思嗜睡量表
多次睡眠潜伏期试验
嗜睡症
白天过度嗜睡
贝克抑郁量表
萧条(经济学)
内科学
睡眠呼吸暂停
阻塞性睡眠呼吸暂停
睡眠障碍
慢波睡眠
睡眠阶段
呼吸暂停-低通气指数
呼吸暂停
呼吸不足
物理疗法
精神科
失眠症
神经学
焦虑
脑电图
经济
宏观经济学
作者
Andrea Iaboni,Dominique Ibañez,Dafna D. Gladman,Murray B. Urowitz,Harvey Moldofsky
出处
期刊:PubMed
日期:2006-12-01
卷期号:33 (12): 2453-7
被引量:22
摘要
To clarify the role of sleep disorders, sleepiness, and depression in patients with systemic lupus erythematosus (SLE) who complain of disabling tiredness.Patients with SLE (31 women, 4 men) with disabling tiredness were evaluated with the Epworth Sleepiness Scale (ESS) and overnight polysomnography, followed by daytime multiple sleep latency tests (MSLT) and the Beck Depression Inventory (BDI). Their polysomnography was compared with 17 healthy, asymptomatic controls.Polysomnography of the patients in comparison with healthy controls showed impaired sleep efficiency (p < 0.02), high arousal frequencies (p < 0.01), increased stage 1 sleep (p < 0.02), decreased stage 3/4 slow-wave sleep (p < 0.02), and a high percentage (77% of patients) with increased alpha-EEG non-REM sleep. In 23% of patients periodic limb movement (PLM) disorder was observed (mean PLM index 31.1 +/- 15); 26% of patients had obstructive sleep apnea (mean apnea/hypopnea index 19.3 +/- 10), and one patient had narcolepsy-cataplexy. Remarkably, 51% of patients were excessively sleepy on both the ESS and MSLT (mean sleep latency < 10 min). This excessive daytime sleepiness was not related to sleep restriction. There was no association between sleepiness and SLE disease features such as neuropsychiatric SLE, medications, fibromyalgia, or disease activity. As a whole, the study group reported mild to moderate depression (mean BDI = 15.8 +/- 9.9). Within the group, the sleepy patients had lower BDI scores than the non-sleepy patients (p < 0.02), and fewer of the sleepy patients were depressed (p < 0.04).Primary sleep disorders, sleepiness, and depression are common in tired SLE patients. Tiredness in SLE that is the result of excessive daytime sleepiness can be distinguished from tiredness of depression. Such distinctions will help identify appropriate treatment for tired patients with SLE.
科研通智能强力驱动
Strongly Powered by AbleSci AI