Abstract Stretchable electronics are an emerging technology critical for applications in wearable health monitors, bio‐integrated devices, and soft robotics. Developing these devices requires compliant conductors that can maintain stable electrical properties under deformation. Metal nanowires (MNWs) dispersed in elastomeric matrices are promising candidates, offering high conductivity, solution processability, and scalability. However, they often suffer from structural and electrical degradation under large or cyclic strains. Recent research has focused on overcoming these electromechanical challenges through innovative structural designs and interfacial engineering. This article summarizes key strategies that enable significant performance improvements, analyzing the mechanisms underpinning enhanced stretchability, conductivity retention, and fatigue resistance. The integration of these robust MNW conductors into practical applications is also critically examined. Finally, ongoing challenges and future research directions are discussed, with a particular emphasis on scalable manufacturing and long‐term operational stability. This article provides a comprehensive overview of recent advancements in high‐performance MNW‐based conductors for next‐generation stretchable and wearable electronic technology.