Abstract Limited by the decoherence of qubits as well as the errors of quantum gates, near-term superconducting quantum computers can only run low-depth quantum circuits to achieve acceptable fidelity. One possible way to overcome these limitations is to construct quantum circuits with additional high-fidelity expressive multi-qubit gates. Recently, a new three-qubit gate, denoted as Controlled-CPHASE-SWAP (CCZS), has been implemented through simultaneous Controlled-Z (CZ) gates. The CCZS gate takes less time than a single CZ gate and can be implemented at the coherence limit. However, how to use the CCZS gate in quantum circuit synthesis remains unexplored. In this paper, we construct the quantum fan-out/parity gates, the controlled-phase gate and the locally fully connected CZ gates with the CCZS gate, respectively. Furthermore, applications of the CCZS gate in quantum error correction, quantum Fourier transform and quantum approximate optimization algorithm are also proposed. We evaluate the performance of the CCZS gate in quantum circuit synthesis through simulation and explore its potential advantages over CZ gates.