Expression and significance of NF-κB and HSP90 in renal puncture tissues and peripheral blood mononuclear cells of patients with lupus nephritis

NF-κ B and HSP90 may play a synergistic role in the pathogenesis of LN. Their elevated expression has a high diagnostic accuracy for LN or SLE without renal damage. Hence, NF-κ B and HSP90 can be used as therapeutic targets and biomarkers for the diagnosis of LN.