微生物学
乳酸
生物
细菌
生物膜
体外
粘附
乳酸菌
食品科学
化学
生物化学
遗传学
有机化学
作者
Heli Anglenius,Harri Mäkivuokko,Ilmari Ahonen,Sofia D. Forssten,Pirjo Wacklin,Jaana Mättö,Sampo J. Lahtinen,Liisa Lehtoranta,Arthur C. Ouwehand
出处
期刊:Microorganisms
[MDPI AG]
日期:2023-01-28
卷期号:11 (2): 329-329
被引量:1
标识
DOI:10.3390/microorganisms11020329
摘要
Traditional probiotics comprise mainly lactic acid bacteria that are safe for human use, tolerate acid and bile, and adhere to the epithelial lining and mucosal surfaces. In this study, one hundred commercial and non-commercial strains that were isolated from human feces or vaginal samples were tested with regards to overall growth in culture media, tolerance to acid and bile, hydrogen peroxide (H2O2) production, and adhesion to vaginal epithelial cells (VECs) and to blood group antigens. As a result, various of the tested lactobacilli strains were determined to be suitable for gastrointestinal or vaginal applications. Commercial strains grew better than the newly isolated strains, but tolerance to acid was a common property among all tested strains. Tolerance to bile varied considerably between the strains. Resistance to bile and acid correlated well, as did VEC adhesion and H2O2 production, but H2O2 production was not associated with resistance to bile or acid. Except for L. iners strains, vaginal isolates had better overall VEC adhesion and higher H2O2 production. Species- and strain-specific differences were evident for all parameters. Rank-ordered clustering with nine clusters was used to identify strains that were suitable for gastrointestinal or vaginal health, demonstrating that the categorization of strains for targeted health indications is possible based on the parameters that were measured in this study.
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