刺
阿尔波特综合征
足细胞
医学
肾脏疾病
肾
免疫学
内科学
生物
内分泌学
肾小球肾炎
蛋白尿
工程类
航空航天工程
作者
Alla Mitrofanova,Antonio Miguel Fontanella,Matthew Tolerico,Shamroop Kumar Mallela,Judith Molina David,Yiqin Zuo,Marcia Boulina,Jin‐Ju Kim,Javier Varona Santos,Mengyuan Ge,Alexis Sloan,Wadih Issa,Margaret Z. Gurumani,Jeffrey D. Pressly,Marie Ito,Matthias Kretzler,Sean Eddy,Robert G. Nelson,Sandra Merscher,George W. Burke
出处
期刊：Journal of The American Society of Nephrology
日期：2022-10-05
卷期号：33 (12): 2153-2173
被引量：71
标识
DOI：10.1681/asn.2021101286
摘要
The activation of the STING pathway acts as a mediator of disease progression in DKD and Alport syndrome. Targeting STING may offer a therapeutic option to treat glomerular diseases of metabolic and nonmetabolic origin or prevent their development, progression, or both.
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