暴发性紫癜
医学
筋膜炎
多器官衰竭
紫癜(腹足类)
重组组织纤溶酶原激活剂
皮肤病科
重症监护医学
外科
缺血
内科学
缺血性中风
生态学
改良兰金量表
生物
作者
P. R. J. Ames,Krsty Nale,Colin Malone
出处
期刊:Blood Coagulation & Fibrinolysis
[Ovid Technologies (Wolters Kluwer)]
日期:2023-03-02
卷期号:34 (4): 247-249
标识
DOI:10.1097/mbc.0000000000001209
摘要
Purpura fulminans is a thrombotic emergency affecting small vessels of skin and of internal organs that may rapidly progress into necrotizing fasciitis, critical limb ischaemia and multiorgan failure; it often develops during an infection or as a postinfective ‘autoimmune’ disorder. Although supportive care and hydration are important, anticoagulation ought to be started to prevent further occlusions alongside blood products according to need. Herein, we describe the case of an elderly woman who received extended intravenous low-dose recombinant tissue plasminogen activator at the onset of purpura fulminans that salvaged her skin and prevented the development of multiorgan failure.
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