医学
特拉维夫
冲程(发动机)
队列
急性中风
队列研究
协议(科学)
物理疗法
物理医学与康复
急诊医学
内科学
病理
替代医学
组织纤溶酶原激活剂
图书馆学
工程类
机械工程
计算机科学
作者
Einor Ben Assayag,Amos D. Korczyn,Nir Giladi,Uri Goldbourt,A. Sholmo Berliner,Shani Shenhar‐Tsarfaty,Efrat Kliper,Hen Hallevi,Ludmila Shopin,Talma Hendler,Dafna Ben Baashat,Orna Aizenstein,Hermona Soreq,Noomi Katz,Zahava Solomon,Anat Mike,Sali Usher,J.M. Hausdorff,Eitan Auriel,Itzhak Shapira,Natan M. Bornstein
标识
DOI:10.1111/j.1747-4949.2011.00652.x
摘要
Recent studies have demonstrated that even survivors of mild stroke experience residual damage, which persists and in fact increases in subsequent years. About 45% of stroke victims remain with different levels of disability. Identifying factors associated with poststroke cognitive and neurological decline could potentially yield more effective therapeutic opportunities.We hypothesize that data based on biochemical, neuroimaging, genetic and psychological measures can, in aggregate, serve as better predictors for subsequent disability, cognitive and neurological deterioration, and suggest possible interventions.The Tel-Aviv Brain Acute Stroke Cohort (TABASCO) study is an ongoing, prospective cohort study that will recruit approximately 1125 consecutive first-ever mild-moderate stroke patients. It is designed to evaluate the association between predefined demographic, psychological, inflammatory, biochemical, neuroimaging and genetic markers, measured during the acute phase, and long-term outcome: subsequent cognitive deterioration, vascular events (including recurrent strokes), falls, affect changes, functional everyday difficulties and mortality.This study is an attempt to comprehensively investigate the long-term outcome of mild-moderate strokes. Its prospective design will provide quantitative data on stroke recurrence, the incidence of other vascular events and the evaluation of cognitive, affective and functional decline. Identifying the factors associated with poststroke cognitive and functional decline could potentially yield more effective therapeutic approaches.
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