Adsorption of bilirubin on the polymeric β-cyclodextrin supported by partially aminated polyacrylamide gel

A β-cyclodextrin resin supported by partially aminated polyacrylamide was synthesized from porous polyacrylamide. The adsorption of bilirubin on the polymeric β-cyclodextrin was investigated in 0.01 M phosphate buffer (pH = 7.4) at 37°C in different conditions with various temperature, pH value, bilirubin concentration and ionic strength, etc. The results indicated that the polymeric β-cyclodextrin was a good adsorbent for unconjugated bilirubin with high capacity.