L-Arginine Combined with Docetaxel Inhibiting Lung Cancer

通过以C57BL/6小鼠腋下接种Lewis肿瘤细胞建立肺癌模型，评估了L-精氨酸(L-Arg)联合多西紫杉醇(DTX)对肺癌的抑制作用。结果表明，空白对照组、L-精氨酸组、多西紫杉醇组、联合用药组平均生存期分别为(24.20 ± 5.87 d)、(28.00 ± 3.09 d)、(29.60 ± 2.90 d)、(35.40 ± 6.26 d)，联合用药组生存期较空白组有显著的延长(n = 6, p By establishing the model of Lewis lung tumor cells injected in C57BL/6 mice, the inhibitory effect of L-arginine (L-Arg) combined with docetaxel (DTX) on lung cancer was evaluated. The results showed that the average survival time of the blank control group, L-arginine group, docetaxel group, and combination drug group was (24.20 ± 5.87 d), (28.00 ± 3.09 d), (29.60 ± 2.90 d), (35.40 ± 6.26 d); the survival of the combined drug group was significantly longer than that of the control group (n = 6, p