医学
冲程(发动机)
睡眠呼吸暂停
持续气道正压
心房颤动
流行病学
低氧血症
睡眠(系统调用)
重症监护医学
气道正压
血压
阻塞性睡眠呼吸暂停
物理疗法
心脏病学
内科学
工程类
操作系统
机械工程
计算机科学
作者
Hsien Lee Lau,Tatjana Rundek,Alberto R. Ramos
标识
DOI:10.1007/s40675-019-00142-1
摘要
This review aims to discuss the most recent data on sleep disorders and stroke, highlighting relevant findings for the practicing neurologist or health providers who encounter patients with sleep disorders and stroke. Sleep apnea and abnormal sleep duration have the strongest association with stroke risk. Possible mechanisms include non-dipping of blood pressure during sleep, hypoxemia, or reoxygenation leading to sympathetic activation, hypertension, atrial fibrillation, and impaired cerebral hemodynamics. Treatment studies suggest that continuous positive airway pressure (CPAP) for sleep apnea could improve primary prevention of stroke, but data is equivocal for secondary prevention. However, CPAP could improve functional outcomes after stroke. Sleep disorders present an opportunity to improve stroke risk and functional outcomes. However, new strategies are needed to determine the patients at high-risk who would most likely benefit from targeted care. Novel methods for phenotyping sleep disorders could provide personalized stroke care to improve clinical outcomes and public health strategies.
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