The expression and significance of VEGF-C and VEGF-D in nasopharyngeal carcinoma

Objective To explore the expressions of VEGF-C and VEGF-D and the correlation with the metastasis through the lymphatic system in nasopharyngeal carcinoma.Method VEGF-C and VEGF-D were labeled by improved immunohistochemical method(S-P), and the relation between their expressions and biological characteristics of nasopharyngeal carcinoma was studied.Result Expressions of VEGF-C and VEGF-D were related to the tumor metastasis through the lymphatic nodes.Conclusion VEGF-C and VEGF-D can regulate the lymphangiogenesis of nasopharyngeal carcinoma and provide scientific theoretical arguments for the therapy of anti-lymphangiogenesis in nasopharyngeal carcinoma patients.