心房颤动
胱抑素C
医学
代谢综合征
内科学
背景(考古学)
心脏病学
肌钙蛋白
肾功能
发病机制
生物标志物
肥胖
心肌梗塞
生物
生物化学
古生物学
作者
Christos Georgakopoulos,Charalambos Vlachopoulos,Georgios Lazaros,Dimitrios Tousoulis
标识
DOI:10.2174/0929867324666171012105528
摘要
Whether the increased atrial fibrillation (AF) risk in metabolic syndrome (MetS) patients is due to the syndrome as a whole or simply the sum of the risks of its individual component parts is still obscure. These two clinical entities share many pathophysiological links and thus distinction between a casual observation and a significant association is difficult. Biomarkers associated with pathogenesis of AF in the context of MetS have the ability to refine future risk prediction. In the present review we identify circulating substances that could be regarded as potential biomarkers for prediction of incident AF, or of cardiovascular events in the setting of AF in patients with MetS. Cardiac myocyte injury and stress markers (troponin and natriuretic peptides), markers of renal function (glomeral filtration rate, cystatin-C), and inflammation markers/mediators (interleukin- 6, CRP) are promising biomarkers of patients with AF and MetS.
科研通智能强力驱动
Strongly Powered by AbleSci AI