纳米纤维
手性(物理)
分子
超分子化学
粘附
细胞粘附
苯丙氨酸
立体化学
生物物理学
化学
材料科学
纳米技术
氨基酸
生物化学
手征对称性
有机化学
物理
生物
量子力学
Nambu–Jona Lasinio模型
夸克
作者
Jinying Liu,F.T. Yuan,Xiaoyü Ma,Dang‐i Y. Auphedeous,Changli Zhao,Chuntai Liu,Changyu Shen,Chuanliang Feng
标识
DOI:10.1002/anie.201801462
摘要
Abstract Although helical nanofibrous structures have great influence on cell adhesion, the role played by chiral molecules in these structures on cells behavior has usually been ignored. The chirality of helical nanofibers is inverted by the odd–even effect of methylene units from homochiral l ‐phenylalanine derivative during assembly. An increase in cell adhesion on left‐handed nanofibers and weak influence of cell behaviors on right‐handed nanofibers are observed, even though both were derived from l ‐phenylalanine derivatives. Weak and negative influences on cell behavior was also observed for left‐ and right‐handed nanofibers derived from d ‐phenylalanine, respectively. The effect on cell adhesion of single chiral molecules and helical nanofibers may be mutually offset.
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