Recommendations for the Usage of Ketamine and Esketamine

Back to table of contents Previous article Next article Letters to the EditorFull AccessRecommendations for the Usage of Ketamine and EsketamineVictor I. Reus, M.D.Victor I. ReusSearch for more papers by this author, M.D.Published Online:2 Dec 2021https://doi.org/10.1176/appi.ajp.2021.21060555AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail TO THE EDITOR: The article by McIntyre et al. (1) aims to synthesize the literature on ketamine and esketamine with respect to efficacy, safety, and tolerability, and to provide guidance for implementation but provides no description of the methodology for the work involved. Given that the extensive disclosure statements reveal that a number of the authors have significant financial interests in the usage of these compounds, several questions arise: How was this “international group of mood disorder experts” selected? How was the work funded? Who wrote the paper and was a professional writing consultant involved? Is there any communication between the editorial and advertising staff regarding planned publication of a given article and simultaneous advertisements by firms marketing the agents under review?Greater transparency regarding these recurrent issues would be a desirable goal.Weill Institute for Neurosciences, University of California San Francisco Send correspondence to Dr. Reus ([email protected]).Reference1 McIntyre RS, Rosenblat JD, Nemeroff CB, et al.: Synthesizing the evidence for ketamine and esketamine in treatment-resistant depression: an international expert opinion on the available evidence and implementation. Am J Psychiatry 2021; 178:383–399Link, Google Scholar FiguresReferencesCited byDetailsCited byTreatment-resistant depression reconsideredSSM - Mental Health, Vol. 2New Insights Into Major Depression and the Treatment of Bipolar DepressionNed H. Kalin, M.D.2 December 2021 | American Journal of Psychiatry, Vol. 178, No. 12 Volume 178Issue 12 December 2021Pages 1129-1129 Metrics PDF download History Published online 2 December 2021 Published in print 1 December 2021