160. Truncated Vesicular Stomatitis Virus G- Protein Improves Baculovirus Transduction Efficiency In Vitro and In Vivo

Pseudotyping of viral vectors has been widely used to enhance viral transduction efficiency. One of the most popular pseudotyping proteins has been the G-protein of the Vesicular Stomatitis Virus, VSV-G. In the present study we show that the 21- amino acid ectodomain with transmembrane and cytoplasmic tail domains of VSV-G (VSV-GED) augments baculovirus-mediated gene-delivery in vertebrate cells.