The sol-gel encapsulation of enzymes

AbstractIn the past decade, the encapsulation of enzymes inside inorganic sol-gel matrices has become a generic method to prepare efficient biocatalysts which are easy to recycle. In this review, the sol-gel processes useful for enzyme encapsulation, (mostly sol-gel silica) are outlined. Then, the most recent developments in the applications of such biocatalysts are presented, in particular regarding biosensors and chemical synthesis. Finally, a special attention is addressed to the types of interactions which are considered to prevail between the enzyme or the substrates and products, and the matrix, in these materials.Keywordssol-gelenzymesimmobilizationapplications