Three New Eremophilenolides from Ligularia hiberniflorum (Makino) Kitam.

Three new eremophilenolides, 3β-angeloyloxy-6β,8α-dimethoxyeremophil-7(11)-en-12,8β-olide, 3β-angeloyloxy-6β-hydroxy-8a-methoxyeremophil-7(11)-en-12,8β-olide and 3β-angeloyloxy-6β-hydroxy-8β-methoxyeremophil-7(11)-en-12,8α-olide, were isolated from the rhizomes of Ligularia hiberniflorum (Makino) Kitam. These structures were elucidated on the basis of spectroscopic evidence. The CD spectra of the compounds are also briefly discussed.