Role For Glycocalyx Perturbation In Atherosclerosis Development And Associated Microvascular Dysfunction

The importance of the endothelial glycocalyx for vascular homeostasis is becoming more and more evident. This review addresses the potential relation between a damaged glycocalyx and the process of atherosclerosis, including the associated impairment in blood-flow regulation. We envision restoration of glycocalyx perturbation in the future as a potential therapy for early treatment of cardiovascular disease.