视神经
眼压
高光谱成像
氧饱和度
眼科
材料科学
眼底(子宫)
饱和(图论)
医学
氧气
化学
地质学
遥感
数学
组合数学
有机化学
作者
Bahram Khoobehi,Hiroyuki Kawano,Jinliang Ning,Claude F. Burgoyne,David A. Rice,Farnaz Ahmad Khan,Hilary W. Thompson,J. M. Beach
摘要
Background and Objective: To evaluate the effect of an acute elevated intraocular pressure (IOP) on oxygen saturation of structures of the optic nerve head. Study Design/Materials and Methods: In the cynomolgus monkey eye, IOP was set to 10 mm Hg, and then raised to 30, 45, and 55 mm Hg. The ONH and overlying vessels were imaged using a fundus camera attached to a hyperspectral imaging system (HSI) at 10 and 30 minutes after IOP elevation. Results: Raising IOP from 10 to 30 mm Hg did not significantly (P < 0.0001) change saturation in vessels or ONH tissue structures but at 55 mm Hg, all structures showed significant reduction. Conclusions: Quantitative assay of the blood oxygen saturation in structures on the surface and overlying the optic nerve head is possible using hyperspectral imaging techniques.
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