材料科学
紫杉醇
癌细胞
癌症研究
转移
转移性乳腺癌
癌症
乳腺癌
循环肿瘤细胞
肿瘤细胞
药物输送
细胞
纳米颗粒
纳米技术
计算机科学
医学
生物
内科学
生物化学
作者
Hongwei Sun,Jinghan Su,Qingshu Meng,Qi Yin,Lingli Chen,Wanyi Gu,Pengcheng Zhang,Zhiwen Zhang,Siling Wang
标识
DOI:10.1002/adma.201602173
摘要
A unique biomimetic drug-delivery system composed of 4T1-breast-cancer-cell membranes and paclitaxel-loaded polymeric nanoparticles (PPNs) (cell-membrane-coated PPNs), demonstrates superior interactions to its source tumor cells and elongated blood circulation, and displays highly cell-specific targeting of the homotypic primary tumor and metastases, with successful inhibition of the growth and lung metastasis of the breast cancer cells. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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