已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

C-reactive protein is associated with low-density lipoprotein cholesterol and obesity in type 2 diabetic Sudanese

2型糖尿病 肥胖 内科学 内分泌学 胆固醇 医学 脂蛋白 糖尿病
作者
Angelo C Dongway,Areeg Faggad,Hani Yousif Zaki,Badreldin Elsonni Abdalla
出处
期刊:Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy [Dove Medical Press]
卷期号:: 427-427 被引量:10
标识
DOI:10.2147/dmso.s85451
摘要

Type 2 diabetes is emerging in Sudan and is associated with obesity. Deregulated lipid metabolism and inflammatory states are suggested risk factors for cardiovascular disease, which is a leading cause of diabetic death. This study aimed to investigate C-reactive protein (CRP) levels and the lipid profile in type 2 diabetic adult Sudanese compared with nondiabetics, and to test their associations with other characteristics.A cross-sectional study including 70 diabetics and 40 nondiabetics was conducted. Anthropometric measurements were assessed, and demographic and medical data were obtained using a structured questionnaire. Blood specimens were collected and biochemical parameters were analyzed applying standard methods.CRP and triglycerides were significantly higher in the diabetic group (P<0.001 and P=0.01, respectively). Differences in total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were not statistically significant between the diabetic and nondiabetic groups. In the diabetic group, correlation analysis revealed that the CRP level had a significant positive correlation with LDL-C (r=0.255, P=0.034) and body mass index (r=0.29, P=0.016). Body mass index showed a significant positive correlation with triglycerides (r=0.386, P=0.001). Within the lipid parameters, a number of significant correlations were observed. Elevated levels of CRP, LDL-C, and triglycerides were markedly more prevalent in the diabetic group of patients. Diabetics showed significantly higher CRP levels compared with nondiabetics (odds ratio 5.56, P=0.001).The high prevalence of obesity among diabetics, together with elevated levels of triglycerides and CRP, suggest coexistence of dyslipidemia and inflammation in diabetes. Our findings emphasize that diabetics were 5.6 times more likely to have high CRP levels than nondiabetics; as CRP is a predictor of cardiovascular disease risk, it can be recognized that diabetics are at more risk of cardiovascular disease than nondiabetics. Considering evaluation of CRP together with the lipid profile in prediction of cardiovascular disease risk in Sudanese diabetics should be further tested in large-scale studies.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
4秒前
8秒前
niko发布了新的文献求助10
12秒前
13秒前
maomao应助丁丁采纳,获得10
15秒前
tao完成签到 ,获得积分10
16秒前
泡泡糖pt发布了新的文献求助10
17秒前
逃离地球完成签到 ,获得积分10
17秒前
失眠的香蕉完成签到 ,获得积分10
19秒前
大方易巧完成签到 ,获得积分10
19秒前
DQ2pi完成签到 ,获得积分10
24秒前
FXT完成签到 ,获得积分10
30秒前
冰封之恋完成签到 ,获得积分10
34秒前
DDGD完成签到 ,获得积分0
37秒前
心灵美的电话完成签到 ,获得积分10
40秒前
44秒前
Jasper应助菠菜采纳,获得10
1分钟前
生动夏青完成签到,获得积分10
1分钟前
香蕉觅云应助生动夏青采纳,获得10
1分钟前
release枫完成签到,获得积分10
1分钟前
1分钟前
一一完成签到,获得积分10
1分钟前
等待的剑身完成签到,获得积分10
1分钟前
草莓熊1215完成签到 ,获得积分10
1分钟前
59完成签到 ,获得积分10
1分钟前
1分钟前
泡泡糖pt完成签到,获得积分20
1分钟前
夏天音符完成签到 ,获得积分10
1分钟前
lemon完成签到 ,获得积分10
1分钟前
南宫古伦发布了新的文献求助10
1分钟前
情怀应助momo采纳,获得10
1分钟前
柯语雪完成签到 ,获得积分10
1分钟前
陈小磊完成签到 ,获得积分10
1分钟前
刘忙完成签到,获得积分10
1分钟前
1分钟前
今后应助充满繁星的夜采纳,获得10
1分钟前
1分钟前
2021完成签到 ,获得积分10
1分钟前
勤奋朋友完成签到 ,获得积分10
1分钟前
momo发布了新的文献求助10
1分钟前
高分求助中
Un calendrier babylonien des travaux, des signes et des mois: Séries iqqur îpuš 1036
Sustainable Land Management: Strategies to Cope with the Marginalisation of Agriculture 1000
Corrosion and Oxygen Control 600
Heterocyclic Stilbene and Bibenzyl Derivatives in Liverworts: Distribution, Structures, Total Synthesis and Biological Activity 500
重庆市新能源汽车产业大数据招商指南(两链两图两池两库两平台两清单两报告) 400
Division and square root. Digit-recurrence algorithms and implementations 400
行動データの計算論モデリング 強化学習モデルを例として 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 有机化学 工程类 生物化学 纳米技术 物理 内科学 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 电极 光电子学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 2545217
求助须知:如何正确求助?哪些是违规求助? 2175578
关于积分的说明 5600050
捐赠科研通 1896314
什么是DOI,文献DOI怎么找? 946155
版权声明 565327
科研通“疑难数据库(出版商)”最低求助积分说明 503541