CuI-Catalyzed Dearomatization/Peroxidation/Cyclization Cascade of Pyrrole-Tethered Indoles

A mild CuI-catalyzed dearomatization/peroxidation/cyclization cascade of pyrrole-tethered indoles has been reached, providing peroxide-incorporated indolizino[8,7-b]indole derivatives in acceptable to good yields (46–76%). Dehydrogenated peroxide can be obtained by the use of a FeCl3/TBHP (tBuOOH)/2,2,2-trifluoroethanol (TFE) system at 50 °C.