吲唑
化学
催化作用
烷基化
级联
级联反应
组合化学
表面改性
药物化学
计算化学
立体化学
有机化学
物理化学
色谱法
作者
Krishna Kanta Das,Asim Kumar Ghosh,Tamanna Mallick,Naznin Ara Begum,Alakananda Hajra
标识
DOI:10.1002/adsc.202201162
摘要
Abstract A Cu(I)‐catalyzed 1,3 oxo alkylation of indazole has been developed for constructing N ‐1‐alkylated indazolone derivatives. This cascade reaction involves the formation of C−N and C−O bonds through the sequential functionalization of N1 and C3 positions of indazole in 41–89% yields. The photo‐physical studies of the synthesized compounds showed efficient quantum yields with high Stoke shift values. The preliminary experimental results suggest an aerobic manifold of the present protocol through single electron transfer. magnified image
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