Assessment of matrix effect in quantitative LC-MS bioanalysis

BioanalysisAhead of Print EditorialAssessment of matrix effect in quantitative LC-MS bioanalysisYunlin Fu, Wenkui Li & Franck PicardYunlin Fu *Author for correspondence: Tel.: +1 862 778 1726; E-mail Address: yunlin.fu@novartis.comhttps://orcid.org/0000-0003-2988-4447Pharmacokinetic Sciences, Novartis Biomedical Research, East Hanover, NJ 07936, USA, Wenkui Li https://orcid.org/0000-0002-1021-2766Pharmacokinetic Sciences, Novartis Biomedical Research, East Hanover, NJ 07936, USA & Franck PicardPharmacokinetic Sciences, Novartis Biomedical Research, CH-4056, Basel, SwitzerlandPublished Online:5 Apr 2024https://doi.org/10.4155/bio-2024-0047AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: LC-MS bioanalysismatrix effect • matrix factor • post-column infusion • post-extraction spiking • pre-extraction spikingReferences1. 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Bioanalysis 12(8), 545–559 (2020).CASGoogle ScholarFiguresReferencesRelatedDetails Ahead of Print STAY CONNECTED Metrics Downloaded 0 times History Received 22 February 2024 Accepted 26 March 2024 Published online 5 April 2024 Information© 2024 Expert Publishing Science Ltd trading as Taylor & FrancisKeywordsLC-MS bioanalysismatrix effect • matrix factor • post-column infusion • post-extraction spiking • pre-extraction spikingFinancial disclosureThe authors have no financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.Competing interests disclosureThe authors have no competing interests or relevant affiliations with any organization or entity with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, stock ownership or options and expert testimony.Writing disclosureNo writing assistance was utilized in the production of this manuscript.PDF download