Liposomal Bupivacaine for Abdominal Fascial Plane Blocks: No Evidence or Lack of Relevant Evidence?

Editorial| May 2024 Liposomal Bupivacaine for Abdominal Fascial Plane Blocks: No Evidence or Lack of Relevant Evidence? This article has an Audio Podcast Ashraf S. Habib, M.B.B.Ch., M.Sc., M.H.Sc., F.R.C.A.; Ashraf S. Habib, M.B.B.Ch., M.Sc., M.H.Sc., F.R.C.A. 1Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina. https://orcid.org/0000-0002-6980-1856 Search for other works by this author on: This Site PubMed Google Scholar Jeffrey Gadsden, M.D.; Jeffrey Gadsden, M.D. 2Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina. Search for other works by this author on: This Site PubMed Google Scholar Brendan Carvalho, M.B.B.Ch., F.R.C.A. Brendan Carvalho, M.B.B.Ch., F.R.C.A. 3Department of Anesthesiology, Stanford University School of Medicine, Palo Alto, California. Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information This editorial accompanies the article on p. 906. Accepted for publication January 29, 2024. Address correspondence to Dr. Habib: Anesthesiology May 2024, Vol. 140, 871–873. https://doi.org/10.1097/ALN.0000000000004933 Connected Content Article: Analgesic Effectiveness of Liposomal Bupivacaine versus Plain Local Anesthetics for Abdominal Fascial Plane Blocks: A Systematic Review and Meta-analysis of Randomized Trials Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Search Site Citation Ashraf S. Habib, Jeffrey Gadsden, Brendan Carvalho; Liposomal Bupivacaine for Abdominal Fascial Plane Blocks: No Evidence or Lack of Relevant Evidence?. Anesthesiology 2024; 140:871–873 doi: https://doi.org/10.1097/ALN.0000000000004933 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll PublicationsAnesthesiology Search Advanced Search Topics: abdomen, bupivacaine, fascia, liposomes Optimizing postoperative analgesia with multimodal, opioid-sparing analgesic protocols is crucial to promote enhanced recovery after surgery. The incorporation of regional anesthetic techniques in those protocols can improve the quality of analgesia and facilitate patient recovery. Fascial plane blocks have been shown to provide useful analgesic benefit after abdominal surgery.1 The duration of analgesia is, however, limited with the use of traditional plain local anesthetics in single shot blocks. Extending the duration of analgesia is desired to prolong the benefits of these blocks. While this can be achieved by using continuous catheter techniques, catheter-based techniques are technically more challenging; require additional time, equipment, and monitoring; incur additional costs; and are associated with leakage and accidental disconnections or dislodgements. Finding ways to prolong the duration of single injection regional blocks has therefore been of interest and includes the addition of adjuncts such as dexamethasone and the use of sustained-release preparations of... You do not currently have access to this content.