多糖
肉桂
卡西亚
化学
抗氧化剂
萃取(化学)
酪氨酸酶
色素沉着
食品科学
色谱法
传统医学
生物化学
医学
酶
中医药
病理
替代医学
作者
Al-Hareth AbdulRaheem Salem Al-Ajalein,Muhammad Hakimin Shafie,Pei-Gee Yap,Mohd Asyraf Kassim,Idanawati Naharudin,Tin Wui Wong,Chee-Yuen Gan
标识
DOI:10.1016/j.ijbiomac.2022.12.023
摘要
The anti-hyperpigmentation effect and tyrosinase inhibitory mechanism of cinnamon polysaccharides have not been reported. The current study focused on the extraction of polysaccharides from Cinnamomum cassia bark using microwave-assisted approach and optimization of the extraction process (i.e., microwave power, irradiation time and buffer-to-sample ratio) by Box-Behnken design to obtain a high yield of polysaccharides with high sun protection factor (SPF), anti-hyperpigmentation and antioxidant activities. The extracted pectic-polysaccharides had low molecular weight and degree of esterification. The optimal extraction process had polysaccharides characterized by (a) monophenolase inhibitory activity = 97.5 %; (b) diphenolase inhibitory activity = 99.4 %; (c) ferric reducing antioxidant power = 4.4 mM; (d) SPF = 6.1; (e) yield = 13.7 %. The SPF, tyrosinase inhibitory and antioxidant activities were primarily contributed by the polysaccharides. In conclusion, the polysaccharides from C. cassia could be an alternative therapeutic source for skin hyperpigmentation treatment.
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