磁共振成像
生物相容性
纳米技术
材料科学
荧光寿命成像显微镜
荧光
生物医学工程
医学
放射科
光学
物理
冶金
作者
Yanhong Zhong,Lin Chen,Shiping Yu,Yongzhen Yang,Xuguang Liu
出处
期刊:ACS Biomaterials Science & Engineering
[American Chemical Society]
日期:2023-11-09
卷期号:9 (12): 6548-6566
被引量:1
标识
DOI:10.1021/acsbiomaterials.3c00988
摘要
Theranostics technology that combines tumor diagnosis or monitoring with therapy is an important direction for the future development of tumor treatment. It takes advantage of efficiently observing tumor tissues, monitoring tumor treatment in real time, and significantly improving the cure efficiency. Magnetic carbon dots (CDs) are of wide interest as molecular imaging probes, drug carriers, photosensitizers, and radiosensitizers in the integration of tumor fluorescence/magnetic resonance bimodal diagnosis and treatment because of their small size, good optical stability, magnetic relaxation rate, and biocompatibility. This review first analyzes and compares the synthesis methods and physicochemical properties of magnetic CDs in recent years and then concludes their mechanism in tumor fluorescence/magnetic resonance bimodal imaging and therapy in details. Subsequently, the research progress of their application in tumor theranostics are summarized. Finally, the problems and challenges of magnetic CDs for development at this stage are prospected. This review provides new ideas for their controlled synthesis and application in efficient and precise therapy for tumors.
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