Climate change is fundamentally reshaping global dryland systems through rising temperatures, altered precipitation regimes, and increased frequency of extreme events. This paper develops a systems-based framework for understanding global desertification as a threshold-driven regime shift in the Earth system. We integrate atmospheric circulation changes, land–atmosphere feedbacks, hydrological disruption, and carbon–dust interactions into a unified conceptual model. Results indicate that global drylands are undergoing synchronized resilience decline, increasing the probability of large-scale ecosystem transitions toward desert states. Keywords Climate change; Aridification; Drylands; Drought; ENSO; Atmospheric circulation; Land-atmosphere feedback; Dust storms; Earth system science; Global change; Vegetation decline; Hydrological cycle; Regime shifts; Tipping points; Desert expansion