医学
肝移植
肝内胆管癌
移植
新辅助治疗
治疗
重症监护医学
外科
内科学
癌症
疾病
乳腺癌
作者
Shankar Logarajah,John Nida,Ève Simoneau,Lavanya Yohanathan
出处
期刊:Hepatoma research
[OAE Publishing Inc.]
日期:2023-08-01
标识
DOI:10.20517/2394-5079.2023.02
摘要
The treatment of intrahepatic cholangiocarcinoma (iCCA) has traditionally been limited to surgical resection or systemic therapy. The role of liver transplantation in the management of iCCA is a topic currently being explored. This paper serves as a review to highlight past, present, and future work being done in regard to liver transplantation for iCCA. Strict protocols with specific selection criteria have shown promising results. Neoadjuvant therapy, locoregional therapy, and immunotherapy are some of the tools that may aid in bridging selected patients with iCCA to liver transplantation. There are currently three ongoing trials designed to further evaluate the efficacy of liver transplantation for iCCA. As criteria continue to be refined and evidence accumulates, liver transplantation may become a suitable option as a curative treatment strategy for highly selected patients with unresectable intraoperative cholangiocarcinoma.
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