Combination treatment with antibiotics and photodynamic therapy in refractory mycobacterium marinum infection: A case report

Mycobacterium marinum can cause skin infection. Treatment of this infection often requires a chronic multidrug regimen. For refractory cases with progression, relapse, or slow recovery, long-term medication may cause problems such as ineffectiveness, poor patient compliance, and drug intolerance. We report a refractory case with a total treatment time of 2 years, successfully cured by the combination of antibiotics and photodynamic therapy. Our case shows that combination treatment with antibiotics and photodynamic therapy may be an effective approach for refractory Mycobacterium marinum infection.