Copper‐Catalyzed C(sp2)−C(sp2) Bond Formation via Single C(sp2)−H Activation

Abstract This review provides a comprehensive overview and evaluation of the studies conducted over the past 15 years into copper catalyzed reactions for C(sp 2 )−C(sp 2 ) bond formation via C(sp 2 )−H activation. The investigations encompass a wide array of starting materials and substrates. The range of substrates studied has been broadened to encompass C−H activation of aryls, heteroaryls, and alkenyl groups. Furthermore, in some cases only catalytic amounts of copper salts were required to drive the challenging C−H functionalization, indicating a promising avenue for future research.