催化作用
骨质疏松症
过程(计算)
化学
化学工程
有机化学
医学
计算机科学
工程类
内科学
操作系统
作者
Wang Jing-cheng,Jing Ye,Guohui Yang,Jiancang Xie,Xinxin Miao,Jianjian Deng,Tianlong Wu,Xigao Cheng,Xiaolei Wang
标识
DOI:10.1002/adhm.202304091
摘要
Abstract Inspired by the Fenton‐like reaction, this work combines copper peroxide (CP) nanoparticles with black phosphorus (BP) nanosheets to form a hydroxyl radical (·OH)‐centered “catalytic” osteogenic system. CP‐produced ·OH interacts with BP to rapidly produce a large amount of phosphate ions, thus accelerating self‐mineralization and promoting bone formation. In turn, BP not only exerts anti‐inflammatory effects, thereby providing a favorable microenvironment for bone formation, but also offsets the potential toxicity of CP induced by reactive oxygen species (ROS). Together with copper ions (Cu 2+ ), phosphate ions are also released as a byproduct of this process, which can contribute to the comprehensive promotion of osteogenesis.
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