电针
刺猬信号通路
刺激
胶质瘤
刺猬
紫杉醇
神经科学
生物
信号转导
医学
药理学
化学
内科学
癌症研究
细胞生物学
针灸科
化疗
病理
替代医学
作者
Congcong Ma,Qinyu Ye,Kecheng Qian,Mengyuan Dai,Lin Gan,Jinding Yang,Zhaoxing Jia,Zixin Pan,Qian Cai,Tianxiang Jiang,Xianming Lin
标识
DOI：10.1016/j.brainresbull.2024.110985
摘要
Paclitaxel (PTX) cannot effectively treat glioma because it cannot cross the bloodbrain barrier (BBB). A specific mode electroacupuncture stimulation (SMES) can temporarily open the BBB, thereby improving drug delivery to the brain. This study aimed to observe SMES-mediated accumulation of PTX in the brain and its anti-glioma effect and explore the role of the Hedgehog pathway.
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