化学
亲核细胞
催化作用
铜
化学计量学
相容性(地球化学)
有机化学
组合化学
化学工程
工程类
作者
Yue Zhao,Bin Fu,Simin Wang,Yanfei Li,Xiuping Yuan,Jie Yin,Tao Xiong,Qian Zhang
出处
期刊:Organic Letters
[American Chemical Society]
日期:2023-04-04
卷期号:25 (14): 2492-2497
被引量:3
标识
DOI:10.1021/acs.orglett.3c00671
摘要
A catalytic defluorinative boroarylation of alkenes with polyfluoroarenes and B2pin2 with the assistance of a PCy3-ligated copper catalyst was developed. Taking advantage of bench-stable alkenes as latent nucleophiles and avoiding traditional reliance on stoichiometric quantities of organometallics, this method showcased good functional group compatibility and proceeded under very mild reaction conditions. A series of valuable boronate-containing polyfluoroarenes including all-carbon quaternary carboncenter-containing triaryl alkylboronates that are otherwise difficult to access were efficiently prepared.
科研通智能强力驱动
Strongly Powered by AbleSci AI