Curved Carbon-Supported Dual-Atom Nanozyme with Ascorbic Acid Oxidase Activity for Cascade Tumor Catalytic Therapy

subsequently fuels its POD-like activity to generate reactive oxygen species, forming an efficient catalytic cascade that induces lipid peroxidation while concurrently depleting glutathione (GSH), thereby achieving potent tumoricidal effects. This work advances the understanding of metal active center construction on highly curved surfaces within carbon support materials, facilitating the development of highly effective nanozyme-based therapeutics.