Photocatalytic C-H Functionalization of Enamides with N-Allylbromodifluoroacetamides via Difluoroamidoalkylation and Difluoroamidosulfonylation

Starting from enamides and N-allylbromodifluoroacetamides, two distinct photocatalyzed cyclization/functionalization strategies have been devised to efficiently introduce a 3,3-difluoro-γ-lactam unit into trifunctionalized enamides. Through these approaches, a collection of 38 trisubstituted...