艰难梭菌
微生物学
艰难梭菌毒素A
半胱氨酸蛋白酶
梭菌
病毒学
微生物毒素
艰难梭菌毒素B
蛋白酶
医学
毒素
生物
抗生素
细菌
生物化学
酶
遗传学
作者
Kristina Oresic Bender,Megan Garland,Jessica A. Ferreyra,Andrew J. Hryckowian,Matthew A. Child,Aaron W. Puri,David E. Solow-Cordero,Steven K. Higginbottom,Ehud Segal,Niaz Banaei,Aimee Shen,Justin L. Sonnenburg,Matthew Bogyo
标识
DOI:10.1126/scitranslmed.aac9103
摘要
A high-throughput screen against the Clostridium difficile toxin B cysteine protease domain identified a drug in clinical trials that reduced C. difficile pathology in a mouse model.
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