医学
抗生素
血流感染
凝固酶
脑脊液
儿科
队列
尿
重症监护
队列研究
重症监护医学
葡萄球菌
金黄色葡萄球菌
内科学
微生物学
细菌
生物
遗传学
作者
Michelle Baczynski,Ashraf Kharrat,Faith Zhu,Xiang Y. Ye,Prakesh S. Shah,Dany E. Weisz,Amish Jain
标识
DOI:10.1016/j.jhin.2021.09.026
摘要
Early antibiotic administration is an important modifiable factor in reducing mortality from late-onset bloodstream infections in preterm infants. In a cohort study including 142 infants with non-coagulase negative staphylococcus bloodstream infection at two tertiary neonatal intensive care units, we identified typical practice-related factors that may be targeted to prevent delays in antibiotic administration. Collection of cerebrospinal fluid or urine sample before administering antibiotics, a longer time taken to site a peripheral intravenous catheter among those without pre-existing access, and a longer time taken to administer fluid boluses were associated with a longer than median time to antibiotic administration.
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