奥马佐单抗
医学
哮喘
恶化
安慰剂
人口
不利影响
儿科
内科学
入射(几何)
随机对照试验
哮喘恶化
重症监护医学
免疫球蛋白E
免疫学
抗体
病理
替代医学
物理
光学
环境卫生
作者
Marc Humbert,Richard Beasley,Jon G. Ayres,Raymond G. Slavin,Jean‐Louis Hébert,Jean Bousquet,K.M. Beeh,Sância Ramos,Giorgio Walter Canonica,S. Hedgecock,H. Fox,Martin Blogg,K. Surrey
出处
期刊:Allergy
[Wiley]
日期:2004-12-20
卷期号:60 (3): 309-316
被引量:1111
标识
DOI:10.1111/j.1398-9995.2004.00772.x
摘要
In patients with inadequately controlled severe persistent asthma, despite high-dose ICS and LABA therapy, and often additional therapy, omalizumab significantly reduced the rate of clinically significant asthma exacerbations, severe exacerbations and emergency visits. Omalizumab is effective and should be considered as add-on therapy for patients with inadequately controlled severe persistent asthma who have a significant unmet need despite best available therapy.
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