水通道蛋白
肺
水通道蛋白1
分泌物
呼吸系统
气道
医学
转基因
水通道蛋白2
生物
细胞生物学
生理学
水道
内科学
生物化学
机械工程
基因
工程类
外科
入口
作者
Yuanlin Song,Linlin Wang,Jian Wang,Chunxue Bai
标识
DOI:10.1007/978-94-024-1057-0_7
摘要
Aquaporins (AQPs ) are water channel proteins supposed to facilitating fluid transport in alveolar space, airway humidification, pleural fluid absorption, and submucosal gland secretion . In this chapter, we mainly focus on the expression of 4 AQPs in the lungs which include AQP1, AQP2 , AQP4 and AQP5 in normal and disease status, and the experience of AQPs function from various model and transgenic mice were summarized in detail to improve our understanding of the role of AQPs in fluid balance of respiratory system. It has been suggested that AQPs play important roles in various physiology and pathophysiology conditions of different lung diseases. There still remains unclear the exact role of AQPs in lung diseases, and thus continuous efforts on elucidating the roles of AQPs in lung physiological and pathophysilogical processes are warranted.
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