Micropatterning of Nafion Membranes on an Electrode Array Using Photolithographic and Lift-off Techniques for Selective Electrochemical Detection and Signal Accumulation

Herein, we present the fabrication of micropatterned Nafion membranes on an electrode array using a combination of photolithographic and lift-off techniques. The Nafion-modified electrodes were applied for selective assays based on the charges of redox compounds. In addition, redox compounds with positive charges were successfully accumulated on the Nafion layers, so that redox signals were improved with the anodic stripping. To the best of our knowledge, this is the first report on micropatterning of Nafion membranes using photolithographic and lift-off techniques.