医学
糖尿病
荟萃分析
心理干预
血压
梅德林
随机对照试验
系统回顾
内科学
临床试验
糖尿病管理
物理疗法
老年学
2型糖尿病
内分泌学
精神科
法学
政治学
作者
Diana Sherifali,Johnny-Wei Bai,Meghan Kenny,Rachel Warren,Muhammad Usman Ali
摘要
Abstract Aim The evidence for self‐management programmes in older adults varies in methodological approaches, and disease criteria. Using predetermined methodological criteria, we evaluated the effect of diabetes‐specific self‐management programme interventions in older adults. Methods The EMBASE , MEDLINE and Cochrane Central Register of Controlled Trials databases were searched from January 1980 to November 2013, as were reference lists from systematic reviews, meta‐analyses and clinical practice guidelines. A total of 13 trials met the selection criteria, which included 4517 older adult participants; 2361 participants randomized to a diabetes self‐management programme and 2156 to usual care. Results The pooled effect on HbA 1c was a reduction of –2 mmol/mol (–0.2%; 95% CI –0.3 to –0.1); tailored interventions [–3 mmol/mol (–0.2%; 95% CI –0.4 to –0.1)] or programmes with a psychological emphasis [–3 mmol/mol (–0.2; 95% CI –0.4 to –0.1)] were most effective. A pooled treatment effect on total cholesterol was a 5.81 mg/dl reduction (95% CI –10.33 to –1.29) and non‐significant reductions in systolic and diastolic blood pressure. Conclusions Diabetes self‐management programmes for older adults demonstrate a small reduction in HbA 1c , lipids and blood pressure. These findings may be of greater clinical relevance when offered in conjunction with other therapies.
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