GC simultaneous determination of camphor,menthol and synthetic borneol in Tongluo Qutong plaster

Objective:To establish the determination method of camphor,menthol and synthetic borneol in Tongluo Qutong plaster.Methods:The sample solution was distilled in volatile oil determination apparatus.Naphthalene was used as the internal standard.HP-INNOWAX capillary column was adopted,nitrogen as the carrier gas,and FID as the detector.The column temperature at 140 ℃.Results:Camphor,menthol and synthetic borneol l(borneol and isborneol) in Tangluo Qutong Plaster and naphthalene have been separated well.The average recovery rates of camphor,menthol and synthetic borneol were 96.2%(RSD=0.78%),96.8%(RSD=0.76%) and 96.9%(RSD=1.4%),respectively.Conclusion:The methord is simple,accurate and separable,and can be used to control the quality of Tongluo Qutong plaster.