The anti-inflammatory and Analgesic Activity of Gutong Film in vivo

Objective:To observe the anti-inflammatory and analgesic activity Gutong film(GTF) in rats.Methods:The anti-inflammatory effect of GTF was observed by the test of paraxylene induced auricle swelling in mice and egg album induced paw edema in rats.The analgesic activity of GF was investigated by the writhing and hot-plate test.Results:GF obviously inhibited the inflammatory edema caused by both inflammatory agents,and significantly elevated the pain threshold,and reduced the writhing frequency induced by acetic acid.Conclusion:GTF has notable effects of anti-inflammatory and analgesic activity.