In situ generation of dihydropyridine for the enantioselective transfer hydrogenation of 1,4-benzoxazines

A new strategy for the enantioselective transfer hydrogenation of benzoxazines involving anin situgeneration of Hantzsch ester has been developed. Dihydroadducts were isolated in good yields (75–99%) and enantioselectivities (89–96% ee).